Promotion of spermatogonial proliferation by neuregulin 1 in newt (Cynops pyrrhogaster) testis

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Promotion of spermatogonial proliferation by neuregulin 1 in newt (Cynops pyrrhogaster) testis

We have previously shown that mammalian follicle-stimulating hormone (FSH) promotes the proliferation of spermatogonia and their differentiation into primary spermatocytes in organ culture of newt testis. In the current study, we performed microarray analysis to isolate local factors secreted from somatic cells upon FSH treatment and acting on the germ cells. We identified neuregulin 1 (NRG1) a...

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The mating season of Japanese newt Cynops pyrrhogaster is generally thought to occur once a year in spring to early summer, during the months of April to June, as in many other Japanese amphibians. However, in fall, from September to October, we often observed breeding colored males demonstrating a mating behavior with females in the field. In this study, in order to identify their true mating ...

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ژورنال

عنوان ژورنال: Mechanisms of Development

سال: 2008

ISSN: 0925-4773

DOI: 10.1016/j.mod.2008.06.004